Attack the Risk Factors-Bone

Research has identified major risk factors that make individuals vulnerabe to chronic bone dysfunction.

 Aging: For most people,  peak bone mass is reached in the mid-twenties.  Bone mass than decreases with additional aging. Accumulation of oxidative stress, mitochondrial dysfunction, poor absorption of vital nutrients are some of the factors that explain aging’s negative effect on bone health. Women especially are sensitive to aging, experiencing a precipitous drop in bone mass around menopause. Inadequate amounts of estrogen shift the balance of bone homeostasis favoring an overall bone resportive state.

 Medical Co-morbidities: Medical conditions such as rheumatoid arthritis, diabetes, and COPD coverage on common pathways to increase the risk of unhealthy bone tissue. Any disease entity that promotes chronic inflammation, excessive oxidative stress, abnormal sugar binding to bone structures, and an acidic environment hastens premature bone aging.

 Gender: Research suggests women have a higher risk of developing bone mass related diseases with a significant uptick post menopause. Estrogen deficiency is a hallmark of menopause. Estrogen inibits the activity of bone resorbing cells, called osteoclasts; and boosts the activity of bone producing cells called, osteoblasts. 

 Malnutrition: Suboptimal intake a key nutrients deprive the body of both the necessary building blocks for robust bones and the body’s natural defenses against factors that accelerate bone decay.

 Lifestyle Choices: Excessive tobacco use, exaggerated alcohol consumption, and chronic emotional stress can magnify the physiologic and biologic processes that lead to enhanced bone resportion and insufficient bone building.

 Inactivity: One of the body’s key mechanisms to induce new bone growth is weight bearing activity. Lack of recreational weight bearing activity, endurance training, and/or resistance training robs the body of a formidable defense against premature bone aging and injury.

The 10 Pillars of Bone Health strategies were designed to attack the risk factors associated with bone disease and to provide a smart and easy approach to promote bone vitality.

 

 Lucas J. Bader MD

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